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The Combination of Metformin and Disulfiram-Cu for Effective Radiosensitization on Glioblastoma Cells

OBJECTIVE: Glioblastoma (GBM) is one of the devastating types of primary brain tumors with a negligible response to standard therapy. Repurposing drugs, such as disulfiram (DSF) and metformin (Met) have shown antitumor properties in different cell lines, including GBM. In the present study, we focus...

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Detalles Bibliográficos
Autores principales: Rezaei, Narges, Neshasteh-Riz, Ali, Mazaheri, Zohreh, Koosha, Fereshteh, Hoormand, Mahmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947006/
https://www.ncbi.nlm.nih.gov/pubmed/31863651
http://dx.doi.org/10.22074/cellj.2020.6798