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A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma

A cogent issue in cancer research is how to account for the effects of tumor microenvironment (TME) on the response to therapy, warranting the need to adopt adequate in vitro and in vivo models. This is particularly relevant in the development of strategies targeting cancer metabolism, as they will...

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Detalles Bibliográficos
Autores principales: Kurelac, Ivana, Abarrategi, Ander, Ragazzi, Moira, Iommarini, Luisa, Ganesh, Nikkitha Umesh, Snoeks, Thomas, Bonnet, Dominique, Porcelli, Anna Maria, Malanchi, Ilaria, Gasparre, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947153/
https://www.ncbi.nlm.nih.gov/pubmed/31835761
http://dx.doi.org/10.3390/jcm8122184