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The Roles of Hypoxia-Inducible Factors and Non-Coding RNAs in Gastrointestinal Cancer
Hypoxia-inducible factors (HIFs) are transcription factors that play central roles in cellular responses against hypoxia. In most cancers, HIFs are closely associated with tumorigenesis by regulating cell survival, angiogenesis, metastasis, and adaptation to the hypoxic tumor microenvironment. Recen...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947354/ https://www.ncbi.nlm.nih.gov/pubmed/31817259 http://dx.doi.org/10.3390/genes10121008 |