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Interferons (IFN-A/-B/-G) Genetic Variants in Patients with Mixed Connective Tissue Disease (MCTD)

Mixed connective tissue disease (MCTD) is a rare complex autoimmune disease in which autoantigens are recognized by endosomal TLRs. Their activation induces a higher secretion of the type I interferons, IFN-γ and the up-regulation of the INF-inducible genes. The present study aimed to investigate wh...

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Detalles Bibliográficos
Autores principales: Paradowska-Gorycka, Agnieszka, Wajda, Anna, Stypinska, Barbara, Walczuk, Ewa, Walczyk, Marcela, Felis-Giemza, Anna, Poluch-Lewandowska, Aleksandra, Olesińska, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947393/
https://www.ncbi.nlm.nih.gov/pubmed/31766529
http://dx.doi.org/10.3390/jcm8122046