AAV Mediated Delivery of Myxoma Virus M013 Gene Protects the Retina against Autoimmune Uveitis

Uveoretinitis is an ocular autoimmune disease caused by the activation of autoreactive T- cells targeting retinal antigens. The myxoma M013 gene is known to block NF-κB (Nuclear Factor kappa-light-chain-enhancer of activated B cells) and inflammasome activation, and its gene delivery has been demons...

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Detalles Bibliográficos
Autores principales: Ridley, Raela B., Young, Brianna M., Lee, Jieun, Walsh, Erin, Ahmed, Chulbul M., Lewin, Alfred S., Ildefonso, Cristhian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947576/
https://www.ncbi.nlm.nih.gov/pubmed/31795515
http://dx.doi.org/10.3390/jcm8122082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947576/
https://www.ncbi.nlm.nih.gov/pubmed/31795515
http://dx.doi.org/10.3390/jcm8122082

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