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Stability and Lability of Parental Methylation Imprints in Development and Disease

DNA methylation plays essential roles in mammals. Of particular interest are parental methylation marks that originate from the oocyte or the sperm, and bring about mono-allelic gene expression at defined chromosomal regions. The remarkable somatic stability of these parental imprints in the pre-imp...

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Detalles Bibliográficos
Autores principales: Farhadova, Sabina, Gomez-Velazquez, Melisa, Feil, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947649/
https://www.ncbi.nlm.nih.gov/pubmed/31810366
http://dx.doi.org/10.3390/genes10120999