Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus

Gene therapy provides an ideal potential treatment for intervertebral disk degeneration by delivering synthetic microRNAs (miRNAs) to regulate the gene expression levels. However, it is very challenging to deliver miRNAs directly, which leads to inactivation, low transfection efficiency, and short h...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Chen, Hao, Zheng, Dandan, Zhang, Hongbo, Deng, Lianfu, Cui, Wenguo, Zhang, Yuhui, Santos, Hélder A., Shen, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947697/
https://www.ncbi.nlm.nih.gov/pubmed/31921568
http://dx.doi.org/10.1002/advs.201902099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947697/
https://www.ncbi.nlm.nih.gov/pubmed/31921568
http://dx.doi.org/10.1002/advs.201902099

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