IL1R2 Blockade Suppresses Breast Tumorigenesis and Progression by Impairing USP15‐Dependent BMI1 Stability

Breast tumor initiating cells (BTICs) with ALDH(+)CD24(−)CD44(+) phenotype are the most tumorigenic and invasive cell population in breast cancer. However, the molecular mechanisms are still unclear. Here, it is found that a negative immune regulator interleukin‐1 receptor type 2 (IL1R2) is upregula...

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Detalles Bibliográficos
Autores principales: Zhang, Lixing, Qiang, Jiankun, Yang, Xiaoli, Wang, Dong, Rehman, Adeel ur, He, Xueyan, Chen, Weilong, Sheng, Dandan, Zhou, Lei, Jiang, Yi‐zhou, Li, Tao, Du, Ying, Feng, Jing, Hu, Xin, Zhang, Jian, Hu, Xi‐chun, Shao, Zhi‐ming, Liu, Suling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947699/
https://www.ncbi.nlm.nih.gov/pubmed/31921558
http://dx.doi.org/10.1002/advs.201901728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947699/
https://www.ncbi.nlm.nih.gov/pubmed/31921558
http://dx.doi.org/10.1002/advs.201901728

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