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Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells

Generation of hematopoietic stem/progenitor cells (HSPCs) via cell expansion or cell reprogramming has been widely achieved by overexpression of transcription factors. Herein, it is reported that without introducing exogenous genes, mouse fibroblasts can be reprogrammed into hemogenic cells based on...

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Detalles Bibliográficos
Autores principales: Zhou, Yi, Zhu, Xingli, Dai, Yuting, Xiong, Shumin, Wei, Chuijin, Yu, Pei, Tang, Yuewen, Wu, Liang, Li, Jianfeng, Liu, Dan, Wang, Yanlin, Chen, Zhu, Chen, Sai‐Juan, Huang, Jinyan, Cheng, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947705/
https://www.ncbi.nlm.nih.gov/pubmed/31921559
http://dx.doi.org/10.1002/advs.201901785