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Notch inhibitor mitigates renal ischemia-reperfusion injury in diabetic rats

Diabetes mellitus can exacerbate renal ischemia-reperfusion (I/R) injury (RI/RI) in diabetic rats. Previous studies have shown that Notch signaling is involved in renal disorders. The aim of the present study was to evaluate the protective effect of the Notch inhibitor γ-secretase N-[N-(3,5-difluoro...

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Detalles Bibliográficos
Autores principales: Duan, Xiaokai, Qin, Guijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947829/
https://www.ncbi.nlm.nih.gov/pubmed/31974606
http://dx.doi.org/10.3892/mmr.2019.10857