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Mitochondrial localization of Dictyostelium discoideum dUTPase mediated by its N-terminus

OBJECTIVE: The nuclear and mitochondrial genomes of Dictyostelium discoideum, a unicellular eukaryote, have relatively high A+T-contents of 77.5% and 72.65%, respectively. To begin to investigate how the pyrimidine biosynthetic pathway fulfills the demand for dTTP, we determined the catalytic proper...

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Detalles Bibliográficos
Autores principales: Chia, Catherine P., Inoguchi, Noriko, Varon, Kyle C., Bartholomai, Bradley M., Moriyama, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947831/
https://www.ncbi.nlm.nih.gov/pubmed/31910901
http://dx.doi.org/10.1186/s13104-019-4879-7