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Anillin regulates breast cancer cell migration, growth, and metastasis by non-canonical mechanisms involving control of cell stemness and differentiation

BACKGROUND: Breast cancer metastasis is driven by a profound remodeling of the cytoskeleton that enables efficient cell migration and invasion. Anillin is a unique scaffolding protein regulating major cytoskeletal structures, such as actin filaments, microtubules, and septin polymers. It is markedly...

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Detalles Bibliográficos
Autores principales: Wang, Dongdong, Naydenov, Nayden G., Dozmorov, Mikhail G., Koblinski, Jennifer E., Ivanov, Andrei I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947866/
https://www.ncbi.nlm.nih.gov/pubmed/31910867
http://dx.doi.org/10.1186/s13058-019-1241-x