Comparison of Bayesian and frequentist group-sequential clinical trial designs

BACKGROUND: There is a growing interest in the use of Bayesian adaptive designs in late-phase clinical trials. This includes the use of stopping rules based on Bayesian analyses in which the frequentist type I error rate is controlled as in frequentist group-sequential designs. METHODS: This paper p...

Descripción completa

Detalles Bibliográficos
Autores principales: Stallard, Nigel, Todd, Susan, Ryan, Elizabeth G., Gates, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947872/
https://www.ncbi.nlm.nih.gov/pubmed/31910813
http://dx.doi.org/10.1186/s12874-019-0892-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947872/
https://www.ncbi.nlm.nih.gov/pubmed/31910813
http://dx.doi.org/10.1186/s12874-019-0892-8

Ejemplares similares