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Comparison of Bayesian and frequentist group-sequential clinical trial designs
BACKGROUND: There is a growing interest in the use of Bayesian adaptive designs in late-phase clinical trials. This includes the use of stopping rules based on Bayesian analyses in which the frequentist type I error rate is controlled as in frequentist group-sequential designs. METHODS: This paper p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947872/ https://www.ncbi.nlm.nih.gov/pubmed/31910813 http://dx.doi.org/10.1186/s12874-019-0892-8 |