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Inhibition of the SIRT1 signaling pathway exacerbates endoplasmic reticulum stress induced by renal ischemia/reperfusion injury in type 1 diabetic rats

The aim of the present study was to investigate whether the diabetic kidney is more susceptible to ischemia/reperfusion (I/R) injury, and identify the potential mechanisms involved. An animal model of type 1 diabetes was created by treating rats with streptozotocin (STZ). This model was then used, a...

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Detalles Bibliográficos
Autores principales: Zhang, Jianjian, Wang, Lei, Gong, Daojing, Yang, Yuanyuan, Liu, Xiuheng, Chen, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947889/
https://www.ncbi.nlm.nih.gov/pubmed/31974604
http://dx.doi.org/10.3892/mmr.2019.10893