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The forces driving clonal expansion of the HIV-1 latent reservoir

Despite antiretroviral therapy (ART) which halts HIV-1 replication and reduces plasma viral load to clinically undetectable levels, viral rebound inevitably occurs once ART is interrupted. HIV-1-infected cells can undergo clonal expansion, and these clonally expanded cells increase over time. Over 5...

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Detalles Bibliográficos
Autores principales: Liu, Runxia, Simonetti, Francesco R., Ho, Ya-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947923/
https://www.ncbi.nlm.nih.gov/pubmed/31910871
http://dx.doi.org/10.1186/s12985-019-1276-8