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Exosomes overexpressing miR-34c inhibit malignant behavior and reverse the radioresistance of nasopharyngeal carcinoma

BACKGROUND: Malignant behavior and radioresistance, which severely limits the efficacy of radiation therapy (RT) in nasopharyngeal carcinoma (NPC), are associated with tumor progression and poor prognosis. Mesenchymal stem cells (MSCs) are used as a therapeutic tool in a variety of tumors. The aim o...

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Detalles Bibliográficos
Autores principales: Wan, Fang-Zhu, Chen, Kai-Hua, Sun, Yong-Chu, Chen, Xi-Chan, Liang, Ren-Ba, Chen, Li, Zhu, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947927/
https://www.ncbi.nlm.nih.gov/pubmed/31915008
http://dx.doi.org/10.1186/s12967-019-02203-z