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Applications of patient-derived tumor xenograft models and tumor organoids
Patient-derived tumor xenografts (PDXs), in which tumor fragments surgically dissected from cancer patients are directly transplanted into immunodeficient mice, have emerged as a useful model for translational research aimed at facilitating precision medicine. PDX susceptibility to anti-cancer drugs...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947974/ https://www.ncbi.nlm.nih.gov/pubmed/31910904 http://dx.doi.org/10.1186/s13045-019-0829-z |