Silencing of Long Non-coding RNA HOTTIP Reduces Inflammation in Rheumatoid Arthritis by Demethylation of SFRP1

Accumulating evidence suggests long non-coding RNAs (lncRNAs) play crucial roles in the pathogenesis of rheumatoid arthritis (RA). Here, we aimed to define the role of HOXA transcript at the distal tip (HOTTIP) in RA pathogenesis in relation to SFRP1 methylation and Wnt signaling pathway. HOTTIP was...

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Detalles Bibliográficos
Autores principales: Hu, Xumin, Tang, Jianhua, Hu, Xuyun, Bao, Peng, Deng, Weixi, Wu, Jionglin, Liang, Yuwei, Chen, Zhipeng, Gao, Liangbin, Tang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948255/
https://www.ncbi.nlm.nih.gov/pubmed/31902746
http://dx.doi.org/10.1016/j.omtn.2019.11.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948255/
https://www.ncbi.nlm.nih.gov/pubmed/31902746
http://dx.doi.org/10.1016/j.omtn.2019.11.015

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