Curculigoside Protects against Excess-Iron-Induced Bone Loss by Attenuating Akt-FoxO1-Dependent Oxidative Damage to Mice and Osteoblastic MC3T3-E1 Cells

SUMMARY: The present investigation found that curculigoside (CUR) can prevent excess-iron-induced bone loss in mice and cells through antioxidation and inhibiting excess-iron-induced phosphorylation of the Akt-FoxO1 pathway. CUR can attenuate the decreasing of cell viability, enhance autophagy, pote...

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Detalles Bibliográficos
Autores principales: Zhang, Quanlong, Zhao, Lu, Shen, Yi, He, Yuqiong, Cheng, Gang, Yin, Ming, Zhang, Qiaoyan, Qin, Luping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948300/
https://www.ncbi.nlm.nih.gov/pubmed/31949885
http://dx.doi.org/10.1155/2019/9281481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948300/
https://www.ncbi.nlm.nih.gov/pubmed/31949885
http://dx.doi.org/10.1155/2019/9281481

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