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Metformin Reduces Lipotoxicity-Induced Meta-Inflammation in β-Cells through the Activation of GPR40-PLC-IP3 Pathway

BACKGROUND AND PURPOSE: Metformin, a widely used antidiabetic drug, has been shown to have anti-inflammatory properties; nevertheless, its influence on β-cell meta-inflammation remains unclear. The following study investigated the effects of metformin on meta-inflammatory in β-cells and whether the...

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Detalles Bibliográficos
Autores principales: Shen, Ximei, Fan, Beibei, Hu, Xin, Luo, Liufen, Yan, Yuanli, Yang, Liyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948338/
https://www.ncbi.nlm.nih.gov/pubmed/31950065
http://dx.doi.org/10.1155/2019/7602427