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Novel data-driven, equation-free method captures spatio-temporal patterns of neurodegeneration in Parkinson's disease: Application of dynamic mode decomposition to PET

Most neurodegenerative disorders are characterized by progressive loss of neurons throughout the course of disease in the form of specific spatio-temporal patterns. To capture and quantify these coherent patterns across both space and time, traditionally one would either fit a pre-defined model with...

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Detalles Bibliográficos
Autores principales: Fu, Jessie Fanglu, Klyuzhin, Ivan S., McKeown, Martin J., Stoessl, A. Jon, Sossi, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948364/
https://www.ncbi.nlm.nih.gov/pubmed/31901793
http://dx.doi.org/10.1016/j.nicl.2019.102150