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Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway

Tamoxifen is a successful endocrine therapy drug for estrogen receptor–positive (ER+) breast cancer. However, resistance to tamoxifen compromises the efficacy of endocrine treatment. In the present study, we identified potential tamoxifen resistance–related gene markers and investigated their mechan...

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Detalles Bibliográficos
Autores principales: Fu, Yijie, Wang, Zhu, Luo, Chuanxu, Wang, Yu, Wang, Yanping, Zhong, Xiaorong, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948370/
https://www.ncbi.nlm.nih.gov/pubmed/31911277
http://dx.doi.org/10.1016/j.tranon.2019.12.005