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Apolipoprotein-AI mimetic peptides D-4F and L-5F decrease hepatic inflammation and increase insulin sensitivity in C57BL/6 mice

BACKGROUND: Apolipoprotein-AI (apo-AI) is the major apolipoprotein found in high density lipoprotein particles (HDLs). We previously demonstrated that apo-AI injected directly into high-fat diet fed mice improved insulin sensitivity associated with decreased hepatic inflammation. While our data prov...

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Detalles Bibliográficos
Autores principales: McGrath, Kristine C., Li, Xiaohong, Twigg, Stephen M., Heather, Alison K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948736/
https://www.ncbi.nlm.nih.gov/pubmed/31914125
http://dx.doi.org/10.1371/journal.pone.0226931