Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis

Cholangiocarcinoma (CCA), a malignant tumor originating in the biliary tract, is well known to be associated with adverse clinical outcomes and high mortality rates due to the lack of effective therapy. Evasion of apoptosis is considered a key contributor to therapeutic success and chemotherapy resi...

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Detalles Bibliográficos
Autores principales: Akara-amornthum, Perawatt, Lomphithak, Thanpisit, Choksi, Swati, Tohtong, Rutaiwan, Jitkaew, Siriporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948742/
https://www.ncbi.nlm.nih.gov/pubmed/31914150
http://dx.doi.org/10.1371/journal.pone.0227454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948742/
https://www.ncbi.nlm.nih.gov/pubmed/31914150
http://dx.doi.org/10.1371/journal.pone.0227454

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