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APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression

Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) DNA cytosine deaminase 3B (A3B) is a DNA editing enzyme which induces genomic DNA mutations in multiple myeloma and in various other cancers. APOBEC family proteins are highly homologous so it is especially difficult to investi...

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Detalles Bibliográficos
Autores principales: Yamazaki, Hiroyuki, Shirakawa, Kotaro, Matsumoto, Tadahiko, Kazuma, Yasuhiro, Matsui, Hiroyuki, Horisawa, Yoshihito, Stanford, Emani, Sarca, Anamaria Daniela, Shirakawa, Ryutaro, Shindo, Keisuke, Takaori-Kondo, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948746/
https://www.ncbi.nlm.nih.gov/pubmed/31914134
http://dx.doi.org/10.1371/journal.pone.0223463