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A genome-wide view of the de-differentiation of central nervous system endothelial cells in culture

Vascular endothelial cells (ECs) derived from the central nervous system (CNS) variably lose their unique barrier properties during in vitro culture, hindering the development of robust assays for blood-brain barrier (BBB) function, including drug permeability and extrusion assays. In previous work...

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Detalles Bibliográficos
Autores principales: Sabbagh, Mark F, Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948952/
https://www.ncbi.nlm.nih.gov/pubmed/31913116
http://dx.doi.org/10.7554/eLife.51276