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Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair

Constitutive heterochromatin is considered as a functionally inert genome compartment, important for its architecture and stability. How such stable structure is maintained is not well understood. Here, we apply four different visualization schemes to label it and investigate its dynamics during DNA...

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Detalles Bibliográficos
Autores principales: Chagin, Vadim O., Reinhart, Britta, Becker, Annette, Mortusewicz, Oliver, Jost, K. Laurence, Rapp, Alexander, Leonhardt, Heinrich, Cardoso, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949026/
https://www.ncbi.nlm.nih.gov/pubmed/31744372
http://dx.doi.org/10.1080/19491034.2019.1688932