Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation

Inducing cardiomyocyte proliferation is a hopeful approach for cardiac regeneration following myocardial infarction. Previous studies have shown that p21 inhibits the cardiomyocyte proliferation and cardiac regeneration. Deacetylation of p21 by Sirt1 deacetylase may reduce p21 abundance and remove p...

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Detalles Bibliográficos
Autores principales: Li, Bing, Li, Mengsha, Li, Xinzhong, Li, Hairui, Lai, Yanxian, Huang, Senlin, He, Xiang, Si, Xiaoyun, Zheng, Hao, Liao, Wangjun, Liao, Yulin, Bin, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949046/
https://www.ncbi.nlm.nih.gov/pubmed/31881009
http://dx.doi.org/10.18632/aging.102587