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Insulin-like growth factor-1 enhances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism

Spinal cord injury (SCI) remains the most common cause of paralysis, and there are no effective therapies for SCI patients. Neural stem cell (NSC)-derived exosomes can attenuate apoptosis and neuroinflammation after traumatic spinal cord injury, but the mechanisms underlying these effects remain unc...

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Detalles Bibliográficos
Autores principales: Ma, Ke, Xu, Huiyou, Zhang, Jian, Zhao, Fei, Liang, Haiqian, Sun, Hongtao, Li, Ping, Zhang, Sai, Wang, Renjie, Chen, Xuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949049/
https://www.ncbi.nlm.nih.gov/pubmed/31848325
http://dx.doi.org/10.18632/aging.102568