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FOXP3 pathogenic variants cause male infertility through affecting the proliferation and apoptosis of human spermatogonial stem cells

Genetic causes of male infertility that is associated with aging are largely unknown. This study was designed to identify novel pathogenic variants of FOXP3 gene causing azoospermia. One homozygous (c.155 G > T) pathogenic variant of FOXP3 was identified in nine non-obstructive azoospermia patien...

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Detalles Bibliográficos
Autores principales: Qiu, Qianqian, Yu, Xing, Yao, Chencheng, Hao, Yujun, Fan, Liqing, Li, Chunyi, Xu, Peng, An, Geng, Li, Zheng, He, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949051/
https://www.ncbi.nlm.nih.gov/pubmed/31855573
http://dx.doi.org/10.18632/aging.102589