Cargando…
FOXP3 pathogenic variants cause male infertility through affecting the proliferation and apoptosis of human spermatogonial stem cells
Genetic causes of male infertility that is associated with aging are largely unknown. This study was designed to identify novel pathogenic variants of FOXP3 gene causing azoospermia. One homozygous (c.155 G > T) pathogenic variant of FOXP3 was identified in nine non-obstructive azoospermia patien...
Autores principales: | Qiu, Qianqian, Yu, Xing, Yao, Chencheng, Hao, Yujun, Fan, Liqing, Li, Chunyi, Xu, Peng, An, Geng, Li, Zheng, He, Zuping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949051/ https://www.ncbi.nlm.nih.gov/pubmed/31855573 http://dx.doi.org/10.18632/aging.102589 |
Ejemplares similares
-
MAP4K4/JNK Signaling Pathway Stimulates Proliferation and Suppresses Apoptosis of Human Spermatogonial Stem Cells and Lower Level of MAP4K4 Is Associated with Male Infertility
por: Wan, Cailin, et al.
Publicado: (2022) -
miRNA-31-5p Mediates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells via Targeting JAZF1 and Cyclin A2
por: Fu, Hongyong, et al.
Publicado: (2018) -
FOXP4 promotes proliferation of human spermatogonial stem cells
por: Luo, Shu-Wei, et al.
Publicado: (2022) -
TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXL
por: Zhou, Dai, et al.
Publicado: (2021) -
OIP5 Interacts with NCK2 to Mediate Human Spermatogonial Stem Cell Self-Renewal and Apoptosis through Cell Cyclins and Cycle Progression and Its Abnormality Is Correlated with Male Infertility
por: Cui, Yinghong, et al.
Publicado: (2023)