The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling

Here we study the effects of differentiated embryonic chondrocyte gene 1(DEC1) deficiency on midbrain dopaminergic(DA) neurons in the substantia nigra pars compacta(SNpc) through behavioral, histological and molecular analysis. We have found that compared to the age-matched WT mice, DEC1 deficient m...

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Detalles Bibliográficos
Autores principales: Zhu, Zhu, Yichen, Wu, Ziheng, Zhang, Dinghao, Ge, Ming, Lu, Wei, Liu, Enfang, Shan, Gang, Hu, Honda, Hiroaki, Jian, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949058/
https://www.ncbi.nlm.nih.gov/pubmed/31884423
http://dx.doi.org/10.18632/aging.102599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949058/
https://www.ncbi.nlm.nih.gov/pubmed/31884423
http://dx.doi.org/10.18632/aging.102599

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