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The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling
Here we study the effects of differentiated embryonic chondrocyte gene 1(DEC1) deficiency on midbrain dopaminergic(DA) neurons in the substantia nigra pars compacta(SNpc) through behavioral, histological and molecular analysis. We have found that compared to the age-matched WT mice, DEC1 deficient m...
Autores principales: | Zhu, Zhu, Yichen, Wu, Ziheng, Zhang, Dinghao, Ge, Ming, Lu, Wei, Liu, Enfang, Shan, Gang, Hu, Honda, Hiroaki, Jian, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949058/ https://www.ncbi.nlm.nih.gov/pubmed/31884423 http://dx.doi.org/10.18632/aging.102599 |
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