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Genome-wide global identification of NRF2 binding sites in A549 non-small cell lung cancer cells by ChIP-Seq reveals NRF2 regulation of genes involved in focal adhesion pathways

Nuclear factor erythroid-derived-2-like 2(NRF2) regulates its downstream genes through binding with antioxidant responsive elements in their promoter regions. Hyperactivation of NRF2 results in oncogenesis and drug resistance in various cancers including non-small cell lung cancer (NSCLC). However,...

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Detalles Bibliográficos
Autores principales: Namani, Akhileshwar, Liu, Kaihua, Wang, Shengcun, Zhou, Xihang, Liao, Yijiao, Wang, Hongyan, Wang, Xiu Jun, Tang, Xiuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949066/
https://www.ncbi.nlm.nih.gov/pubmed/31884422
http://dx.doi.org/10.18632/aging.102590