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Probabilistic cell typing enables fine mapping of closely related cell types in situ
Understanding the function of a tissue requires knowing the spatial organization of its constituent cell types. In the cerebral cortex, single-cell RNA sequencing (scRNA-seq) has revealed the genome-wide expression patterns that define its many, closely related neuronal types, but cannot reveal thei...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949128/ https://www.ncbi.nlm.nih.gov/pubmed/31740815 http://dx.doi.org/10.1038/s41592-019-0631-4 |