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Probabilistic cell typing enables fine mapping of closely related cell types in situ

Understanding the function of a tissue requires knowing the spatial organization of its constituent cell types. In the cerebral cortex, single-cell RNA sequencing (scRNA-seq) has revealed the genome-wide expression patterns that define its many, closely related neuronal types, but cannot reveal thei...

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Detalles Bibliográficos
Autores principales: Qian, Xiaoyan, Harris, Kenneth D., Hauling, Thomas, Nicoloutsopoulos, Dimitris, Muñoz-Manchado, Ana B., Skene, Nathan, Hjerling-Leffler, Jens, Nilsson, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949128/
https://www.ncbi.nlm.nih.gov/pubmed/31740815
http://dx.doi.org/10.1038/s41592-019-0631-4