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Personalized neoantigen-pulsed dendritic cell vaccines show superior immunogenicity to neoantigen-adjuvant vaccines in mouse tumor models

Development of personalized cancer vaccines based on neoantigens has become a new direction in cancer immunotherapy. Two forms of cancer vaccines have been widely studied: tumor-associated antigen (including proteins, peptides, or tumor lysates)-pulsed dendritic cell (DC) vaccines and protein- or pe...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Yuan, Fengjiao, Shu, Yang, Tian, Yaomei, Zhou, Bailing, Yi, Linglu, Zhang, Xueyan, Ding, Zhenyu, Xu, Heng, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949210/
https://www.ncbi.nlm.nih.gov/pubmed/31807878
http://dx.doi.org/10.1007/s00262-019-02448-z