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DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells

DNA damage-induced apoptosis suppressor (DDIAS) regulates cancer cell survival. Here we investigated the involvement of DDIAS in IL-6–mediated signaling to understand the mechanism underlying the role of DDIAS in lung cancer malignancy. We showed that DDIAS promotes tyrosine phosphorylation of signa...

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Detalles Bibliográficos
Autores principales: Im, Joo-Young, Kim, Bo-Kyung, Lee, Kang-Woo, Chun, So-Young, Kang, Mi-Jung, Won, Misun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949220/
https://www.ncbi.nlm.nih.gov/pubmed/31900385
http://dx.doi.org/10.1038/s41389-019-0187-2