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N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells

SGK196 is a protein O-mannose kinase involved in an indispensable phosphorylation step during laminin-binding glycan synthesis on alpha-dystroglycan (α-DG). However, the function of SGK196 in cancer diseases remains elusive. In the current study, we demonstrated that SGK196 is primarily modified by...

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Detalles Bibliográficos
Autores principales: Xu, Ci, Zhang, Meichao, Bian, Lei, Li, Yanyan, Yao, Yuan, Li, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949223/
https://www.ncbi.nlm.nih.gov/pubmed/31913260
http://dx.doi.org/10.1038/s41389-019-0188-1