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Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions
Recent high-throughput transcription factor (TF) binding assays revealed that TF cooperativity is a widespread phenomenon. However, a global mechanistic and functional understanding of TF cooperativity is still lacking. To address this, here we introduce a statistical learning framework that provide...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949242/ https://www.ncbi.nlm.nih.gov/pubmed/31913281 http://dx.doi.org/10.1038/s41467-019-13888-7 |