Metal ions and sugar puckering balance single-molecule kinetic heterogeneity in RNA and DNA tertiary contacts

The fidelity of group II intron self-splicing and retrohoming relies on long-range tertiary interactions between the intron and its flanking exons. By single-molecule FRET, we explore the binding kinetics of the most important, structurally conserved contact, the exon and intron binding site 1 (EBS1...

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Detalles Bibliográficos
Autores principales: Steffen, Fabio D., Khier, Mokrane, Kowerko, Danny, Cunha, Richard A., Börner, Richard, Sigel, Roland K. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949254/
https://www.ncbi.nlm.nih.gov/pubmed/31913262
http://dx.doi.org/10.1038/s41467-019-13683-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949254/
https://www.ncbi.nlm.nih.gov/pubmed/31913262
http://dx.doi.org/10.1038/s41467-019-13683-4

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