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Development of a novel anti-hepatitis B virus agent via Sp1

Nucleos(t)ide analog (NA) therapy has proven effective in treating chronic hepatitis B. However, NAs frequently result in viral relapse after the cessation of therapy. This is because NAs cannot fully eliminate the viral episomal covalently closed circular DNA (cccDNA) in the nucleus. In this study,...

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Detalles Bibliográficos
Autores principales: Hayakawa, Michiyo, Umeyama, Hideaki, Iwadate, Mitsuo, Taguchi, Y.-H., Yano, Yoshihiko, Honda, Takashi, Itami-Matsumoto, Saori, Kozuka, Ritsuzo, Enomoto, Masaru, Tamori, Akihiro, Kawada, Norifumi, Murakami, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949255/
https://www.ncbi.nlm.nih.gov/pubmed/31913341
http://dx.doi.org/10.1038/s41598-019-56842-9