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Development of a novel anti-hepatitis B virus agent via Sp1
Nucleos(t)ide analog (NA) therapy has proven effective in treating chronic hepatitis B. However, NAs frequently result in viral relapse after the cessation of therapy. This is because NAs cannot fully eliminate the viral episomal covalently closed circular DNA (cccDNA) in the nucleus. In this study,...
Autores principales: | Hayakawa, Michiyo, Umeyama, Hideaki, Iwadate, Mitsuo, Taguchi, Y.-H., Yano, Yoshihiko, Honda, Takashi, Itami-Matsumoto, Saori, Kozuka, Ritsuzo, Enomoto, Masaru, Tamori, Akihiro, Kawada, Norifumi, Murakami, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949255/ https://www.ncbi.nlm.nih.gov/pubmed/31913341 http://dx.doi.org/10.1038/s41598-019-56842-9 |
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