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Integrin-specific hydrogels modulate transplanted human bone marrow-derived mesenchymal stem cell survival, engraftment, and reparative activities

Stem cell therapies are limited by poor cell survival and engraftment. A hurdle to the use of materials for cell delivery is the lack of understanding of material properties that govern transplanted stem cell functionality. Here, we show that synthetic hydrogels presenting integrin-specific peptides...

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Detalles Bibliográficos
Autores principales: Clark, Amy Y., Martin, Karen E., García, José R., Johnson, Christopher T., Theriault, Hannah S., Han, Woojin M., Zhou, Dennis W., Botchwey, Edward A., García, Andrés J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949269/
https://www.ncbi.nlm.nih.gov/pubmed/31913286
http://dx.doi.org/10.1038/s41467-019-14000-9