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Integrin-specific hydrogels modulate transplanted human bone marrow-derived mesenchymal stem cell survival, engraftment, and reparative activities
Stem cell therapies are limited by poor cell survival and engraftment. A hurdle to the use of materials for cell delivery is the lack of understanding of material properties that govern transplanted stem cell functionality. Here, we show that synthetic hydrogels presenting integrin-specific peptides...
Autores principales: | Clark, Amy Y., Martin, Karen E., García, José R., Johnson, Christopher T., Theriault, Hannah S., Han, Woojin M., Zhou, Dennis W., Botchwey, Edward A., García, Andrés J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949269/ https://www.ncbi.nlm.nih.gov/pubmed/31913286 http://dx.doi.org/10.1038/s41467-019-14000-9 |
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