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Non-invasive molecular tracking method that measures ocular drug distribution in non-human primates

Intravitreal (IVT) injection has become the standard route for drug administration in retinal diseases. However, the ability to measure biodistribution of ocular therapeutics in large species remains limited, due to the invasive nature of some techniques or their lack of spatial information. The aim...

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Detalles Bibliográficos
Autores principales: Normand, Guillaume, Maker, Michael, Penraat, Jan, Kovach, Kellyann, Ghosh, Joy G., Grosskreutz, Cynthia, Chandra, Sudeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949284/
https://www.ncbi.nlm.nih.gov/pubmed/31925329
http://dx.doi.org/10.1038/s42003-019-0731-9