VPS35 regulates tau phosphorylation and neuropathology in tauopathy

The vacuolar protein sorting 35 (VPS35) is a major component of the retromer recognition core complex which regulates intracellular protein sorting and trafficking. Deficiency in VPS35 by altering APP/Aβ metabolism has been linked to late-onset Alzheimer’s disease. Here we report that VPS35 is signi...

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Detalles Bibliográficos
Autores principales: Vagnozzi, Alana N., Li, Jian-Guo, Chiu, Jin, Razmpour, Roshanak, Warfield, Rebecca, Ramirez, Servio H., Praticò, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949432/
https://www.ncbi.nlm.nih.gov/pubmed/31289348
http://dx.doi.org/10.1038/s41380-019-0453-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949432/
https://www.ncbi.nlm.nih.gov/pubmed/31289348
http://dx.doi.org/10.1038/s41380-019-0453-x

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