Neutrophils suppress tumor‐infiltrating T cells in colon cancer via matrix metalloproteinase‐mediated activation of TGFβ

High T‐cell infiltration in colorectal cancer (CRC) correlates with a favorable disease outcome and immunotherapy response. This, however, is only observed in a small subset of CRC patients. A better understanding of the factors influencing tumor T‐cell responses in CRC could inspire novel therapeut...

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Detalles Bibliográficos
Autores principales: Germann, Markus, Zangger, Nadine, Sauvain, Marc‐Olivier, Sempoux, Christine, Bowler, Amber D, Wirapati, Pratyaksha, Kandalaft, Lana E, Delorenzi, Mauro, Tejpar, Sabine, Coukos, George, Radtke, Freddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949488/
https://www.ncbi.nlm.nih.gov/pubmed/31793740
http://dx.doi.org/10.15252/emmm.201910681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949488/
https://www.ncbi.nlm.nih.gov/pubmed/31793740
http://dx.doi.org/10.15252/emmm.201910681

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