Glutathione peroxidase 8 negatively regulates caspase‐4/11 to protect against colitis

Human caspase‐4 and its mouse homolog caspase‐11 are receptors for cytoplasmic lipopolysaccharide. Activation of the caspase‐4/11‐dependent NLRP3 inflammasome is required for innate defense and endotoxic shock, but how caspase‐4/11 is modulated remains unclear. Here, we show that mice lacking the ox...

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Detalles Bibliográficos
Autores principales: Hsu, Jye‐Lin, Chou, Jen‐Wei, Chen, Tzu‐Fan, Hsu, Jeh‐Ting, Su, Fang‐Yi, Lan, Joung‐Liang, Wu, Po‐Chang, Hu, Chun‐Mei, Lee, Eva Y‐HP, Lee, Wen‐Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949489/
https://www.ncbi.nlm.nih.gov/pubmed/31782617
http://dx.doi.org/10.15252/emmm.201809386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949489/
https://www.ncbi.nlm.nih.gov/pubmed/31782617
http://dx.doi.org/10.15252/emmm.201809386

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