Cargando…

Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis

Molecular programs involved in embryogenesis are frequently upregulated in oncogenic dedifferentiation and metastasis. However, their precise roles and regulatory mechanisms remain elusive. Here, we showed that CDK1 phosphorylation of TFCP2L1, a pluripotency‐associated transcription factor, orchestr...

Descripción completa

Detalles Bibliográficos
Autores principales: Heo, Jinbeom, Noh, Byeong‐Joo, Lee, Seungun, Lee, Hye‐Yeon, Kim, YongHwan, Lim, Jisun, Ju, Hyein, Yu, Hwan Yeul, Ryu, Chae‐Min, Lee, Peter CW, Jeong, Hwangkyo, Oh, Yumi, Kim, Kyunggon, Kim, Sang‐Yeob, Son, Jaekyoung, Hong, Bumsik, Kim, Jong Soo, Cho, Yong Mee, Shin, Dong‐Myung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949511/
https://www.ncbi.nlm.nih.gov/pubmed/31709755
http://dx.doi.org/10.15252/emmm.201910880